In the United States, much of our excess calorie intake doesn’t come from food, it comes from beverages. Sweetened drinks are heavily marketed, inexpensive, and widely available, which makes drinking calories feel normal. But this shift has dramatically affected health, fueling rising rates of obesity and type 2 diabetes (T2DM). Understanding how we got here, and where healthier sweeteners fit in, can help us rethink what’s in our cup.
The Rise of High-Fructose Corn Syrup in the American Diet
High-fructose corn syrup (HFCS) didn’t always dominate our food supply. In the 1970s, rising sugar costs and agricultural policy changes made corn-based sweeteners cheaper to produce. Food manufacturers embraced High-fructose corn syrup because it was sweet, shelf-stable, and highly profitable. Within two decades, High-fructose corn syrup made its way into soda, baked goods, condiments, breads, cereal, and even “health foods.”
High-fructose corn syrup is not dramatically different from table sugar (both contain glucose and fructose), but its high fructose content and liquid form make overconsumption easy. Unlike glucose, which signals fullness, fructose does not trigger satiety hormones, and it is rapidly stored in the liver as fat. Heavy fructose intake is linked to increased liver fat, insulin resistance, elevated triglycerides, and visceral obesity.
As sweetened beverage consumption soared, so did disease rates. Studies repeatedly show that adults and children who drink sugary beverages have a significantly higher risk of obesity and type 2 diabetes — independent of calorie intake from food. In short: liquid calories are uniquely harmful.
Why Drinking Calories is So Problematic
Sugary beverages deliver calories without nutrients, fiber, or protein. They hit the bloodstream fast and bypass the body’s appetite control mechanisms. When you drink a soda or sweetened coffee, you don’t compensate by eating less food later — you simply add more calories to your day.
A 12-ounce soda contains roughly 150 calories and up to 9 teaspoons of sugar. A typical large sugary coffee drink or smoothie can exceed 400–600 calories. Over time, this contributes to weight gain, fatty liver, and metabolic disease.
Artificial Sweeteners Aren’t the Perfect Fix
Many people turn to “diet” beverages to cut calories, but research shows that artificial sweeteners may not solve the problem.
Artificial sweeteners — such as aspartame, sucralose (Splenda), and saccharin — are calorie-free, but they can stimulate insulin secretion, alter the gut microbiome, and increase cravings for sweet foods. Some studies suggest that regular consumption is linked to weight gain, metabolic dysfunction, and increased risk of type 2 diabetes — even in people who don’t consume excess calories.
Why? The body may interpret sweetness as a signal that calories are coming, triggering insulin release. When calories don’t arrive, this mismatch may worsen insulin resistance and encourage overeating later.
In other words, the problem isn’t just the calories — it’s the sweetness itself.
So What Are Safe Sweeteners?
Not all sweeteners are harmful. Some provide sweetness without the metabolic chaos. Better
options include:
- Stevia: A natural, zero-calorie sweetener from the stevia plant. It does not raise blood sugar or insulin levels and may even improve glucose tolerance.
- Monk Fruit (Luo Han Guo): Another natural, no-calorie sweetener with minimal metabolic effects. It’s very sweet, so a little goes a long way.
- Allulose: A low-calorie sweetener that behaves more like sugar in baking. It may reduce post-meal glucose and insulin.
- Erythritol: A sugar alcohol that provides sweetness with minimal calories. Most people tolerate it well, though high doses can cause GI upset.
These options aren’t perfect — and whole foods are always best — but they are far safer than
sugar, High-fructose corn syrup, and artificial sweeteners.
Practical Tips to Cut Liquid Calories
Small changes add up:
- Choose water, sparkling water, or unsweetened tea
- Flavor with citrus, cucumber, or herbs
- Swap soda for flavored seltzer
- Replace energy drinks with cold brew
- Limit “coffee desserts” — lattes, frappes, and sweet cream drinks
- Read labels; sugar hides everywhere
Aim to make sweet drinks the exception, not the habit.
A Simpler Way to Look at It
Every day, we make dozens of small choices that shape our health. One of the most powerful choices is what we drink. Liquid sugar — whether from high-fructose corn syrup, cane sugar, or artificial sweeteners — rewires metabolism in ways that promote weight gain and diabetes. By choosing beverages that nourish rather than disrupt, we support healthier blood sugar, better energy, and a lower risk of chronic disease.
References
- Bray, G., et al. “Consumption of high-fructose corn syrup in beverages may play a role in
the epidemic of obesity.” American Journal of Clinical Nutrition. https://pubmed.ncbi.nlm.nih.gov/15051594/ - Malik, V., et al. “Sugar-sweetened beverages and risk of metabolic syndrome and type 2
diabetes.” Diabetes Care. https://diabetesjournals.org/care/article/33/11/2477/26589/Sugar-Sweetened-Beverages-and-Risk-of-Metabolic - Azad, M., et al. “Artificial sweeteners and metabolic health.” CMAJ.
- Rojas, J., et al. “Fructose and metabolic syndrome.” Journal of Endocrinology.

